Abstract

old, were i.p. inoculated with 2 x 10 5 trypomastigotes blood stream of T. cruzi (Colombian, Y, Bolivia or RC strains). The results allow to conclude that the T. cruzi infection affect the intrauterine growth of the mouse fetus, with reduction of both weight and length, umbilical cord length, body weight to placenta weight ratio and body weight to umbilical cord length ratio. T. cruzi strains showed different behavior. In general, the less prejudicial to the fetal growth was the RC strain, whereas the most prejudicial were the Bolivia and Y strains. The parasitemic curves of these strains show the most rapid growth, reaching the peak at the 5th and 7th day, respectively. As inoculation was made to agree the last pregnancy day with the parasitemic peak, the infected animals had the most rapid infection with elevated parasitemy, without possibility of maternal adaptation.

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