Abstract

Drug prices are innately dynamic, yet conventional economic evaluation assumes a constant price over time. Some healthcare technology assessment agencies, including the Institute for Clinical and Economic Review, do permit the inclusion of life-cycle drug pricing (LCDP) under certain circumstances. However, little guidance is given when this should be implemented and how it should be done. Our aim was to identify methods of incorporating LCDP into cost-effectiveness models, and characterize the current state-of-the-art.

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