Abstract
Editorial: "Thyroid Hormone in Brain and Brain Cells".
Highlights
Thyroid hormones (TH) function in brain has been known for a very long time
In 1813, Jean-François Coindet, a Swiss physician, made the discovery that iodine was efficient at treating goiter and cretinism, a disease associated to mental retardation, which was endemic in his country
It is well established that most brain cell types need TH for a proper and timely differentiation
Summary
Thyroid hormones (TH) function in brain has been known for a very long time. In 1813, Jean-François Coindet, a Swiss physician, made the discovery that iodine was efficient at treating goiter and cretinism, a disease associated to mental retardation, which was endemic in his country. It revealed a number of other functions for TH, during development and in adult brain. One key aspect of the neurodevelopmental function of TH, bringing major complications, is that TH does not freely circulate in all brain areas and cell types, as originally postulated.
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