Abstract
Editorial: Ion Channels of Mature Human Erythrocytes
Highlights
As an example, circulating erythrocytes are cellular sensors of the oxygen tension and mechanical stress
This special issue of The Open Biology Journal focuses on ion channels in the membrane of mature human erythrocytes, their regulation and their putative functions
Mature human erythrocytes activate organic osmolyte and anion channels via ATP release and autocrine purinergic signaling which is reminiscent of the activation of osmolyte channels in nucleated cells upon cell swelling
Summary
As an example, circulating erythrocytes are cellular sensors of the oxygen tension and mechanical stress. Devoid of nuclei and mitochondria, mature mammalian erythrocytes maintain a full set of functional ion channels in their plasma membrane. This special issue of The Open Biology Journal focuses on ion channels in the membrane of mature human erythrocytes, their regulation and their putative functions.
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