Abstract

We are excited to publish this special issue of JMT devoted to the proceedings of a 1-day symposium organized by the American College of Medical Toxicology (ACMT) at the CDC Conference Center in Chamblee GA on February 29, 2012 entitled “Use and Misuse of Metal Chelation Therapy.” ACMT and the editorial board of JMT thank Dr. Charles McKay for his efforts as the guest editor of this chelation issue. Because these papers were all prepared from transcripts from the conference, some contain colloquial expressions; however, edits were made to improve the language where appropriate. All of the following manuscripts underwent blinded peer review: Current use of chelation in American Healthcare Public Health Department response to mercury poisoning: the importance of biomarkers and risks and benefits analysis for chelation therapy Recommendations for provoked challenge urine testing The scientific basis for chelation: animal studies and lead chelation Role of chelation in the treatment of lead poisoning: discussion of the treatment of lead-poisoned children trial (TLC) The role of chelation in the treatment of arsenic and mercury poisoning The role of chelation in the treatment of other metal poisonings Medical toxicology case presentations: to chelate or not to chelate, is that the question? Federal Regulation of Unapproved Chelation Products Various COIs were declared and are listed in each article. Any reports made by employees of government agencies represent findings and conclusions of the author(s) and do not necessarily represent the official position of the government agency. Any figures that were reproduced were done so after the appropriate permissions were obtained. ACMT and JMT want to acknowledge and give thanks to Lynn Lancaster, MS, CIH (ret), grant manager/grant writer for ACMT, for all of her assistance, including tracking all articles through the editorial and publication process, for collecting all conflict of interest statements, and for uploading all of the original manuscripts and revisions. We also acknowledge Kavitha C. Reinhold, MA, freelance medical editor/writer, Chicago, Illinois for her editing of the following articles: Use of chelation in American Healthcare Federal regulation of unapproved chelation products Chelation during pregnancy in the lead poisoned patient Role of chelation in the treatment of lead poisoning: discussion of the treatment of lead-exposed children trial (TLC) Public Health Department response to mercury poisoning: the importance of biomarkers and risks and benefits analysis for chelation therapy

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