Abstract

Objectives: To calculate the incidence of ectopic pregnancy in cases with recurrent early pregnancy loss and cases of recurrent implantation failure. Methods and materials: This is a retrospective cohort study. 200 women were recruited from the infertility clinic at shat by maternity university hospital seeking fertility. 100 of them were with history of recurrent implantation failure (RIF) and 100 with history of recurrent pregnancy loss (RPL). Revisiting their hospital files for the history of ectopic pregnancy was done. Results: 8% of cases of RPL had history of ectopic pregnancy while only 6% of cases of RIF had the history. There was no significant difference between the two groups (p = 0.579). There was significantly higher incidence of ectopic pregnancy in both groups if compared with the general population (p = 0.0001 and 0.043) in RPL and RIF consecutively. Conclusions: RPL and RIF may be considered as a risk factor for ectopic pregnancy.

Highlights

  • Ectopic pregnancy (EP) refers to the blastocyst implantation outside the uterine cavity endometrium with over 92.5% implanting in the fallopian tube [1] [2]

  • To calculate the incidence of ectopic pregnancy in cases with recurrent early pregnancy loss and cases of recurrent implantation failure. This is a retrospective cohort study. 200 women were recruited from the infertility clinic at shat by maternity university hospital seeking fertility. 100 of them were with history of recurrent implantation failure (RIF) and 100 with history of recurrent pregnancy loss (RPL)

  • The aim of this study is to evaluate the risk of ectopic pregnancy in cases with RIF and RPL

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Summary

Introduction

Ectopic pregnancy (EP) refers to the blastocyst implantation outside the uterine cavity endometrium with over 92.5% implanting in the fallopian tube [1] [2]. The incidence of EP in the UK (11.1/1000 pregnancies) is similar to that in other countries, such as Norway (14.9/1000) and Australia (16.2/1000) [3]. Women with a previous history of EP have an increased risk [12]. Some types of contraception, such as progestogen-only contraception and the intrauterine contraceptive device, are associated with an increased incidence of EP when there is contraceptive failure without necessarily increasing the absolute risk of EP [13]

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