Abstract

Based on the available results of the conducted studies, it can be said that the current level of influence of negative environmental factors has exceeded the critical level of the adaptive capabilities of the body of women of fertile age. This determines the fundamental applied importance of identifying the influence of individual factors and the consequences of the use of pesticides on the incidence of cervical erosion, which is an endogenous risk factor for the development of malignant neoplasms of the cervix. In the course of the work, an assessment was made of the independent, total and combined effect of mineral fertilizers and agrochemicals on indicators of the incidence of cervical erosion in women in rural areas of the Republic of Dagestan, since they are the leading environmental factors. A two-way analysis of variance was carried out for the influence of the place of residence and the intensity of the use of mineral fertilizers and agrochemicals. In total, information was obtained on the effect of over 600 combinations of mineral fertilizers and pesticides on the incidence of cervical erosion in women in rural areas of the Republic of Dagestan. The influence of natural and anthropogenic ecological and hygienic factors in the Republic of Dagestan on the incidence of cervical erosion (ESM) in the adult female population, especially in rural areas of the republic, was established. The analyzed data on the impact of the use of mineral fertilizers and pesticides demonstrate that in rural regions, where there is an intensive rate of development of agriculture with the use of mineral fertilizers and pesticides, it is necessary to take them into account as real risk factors for the development of cervical erosion in women. The results of the study give grounds to assume the presence of an indirect influence of the considered environmental factors on the incidence of cervical erosion.

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