Eco-friendly synthesis, characterization, catalytic, antibacterial, antidiabetic, and antioxidant activities of Embelia robusta seeds extract stabilized AgNPs

Abstract

The current research study is to develop and easy and eco-friendly method for the synthesis of AgNPs using aqueous seed extract of Embelia robusta (Er-AgNPs) and evaluated the extract to know the effects of catalytic, anti-bacterial, anti-diabetic, and anti-oxidant activity. Er-AgNPs were characterized via several techniques including UV-vis absorption, PL, XRD, FTIR, and TEM UV-vis study confirmed the formation of Er-AgNPs. Face centered cubic (FCC) crystal structure of biosynthesized Er-AgNPs was governed by the XRD analysis. FTIR study confirmed the presence of OH and NH functional groups of secondary molecules of seed extract capped on the AgNPs surface. The produced Er-AgNPs were dark brown in color with almost spherical shape in the size ranging from 5 to 15 nm. The presence of Er-AgNPs (1 mL) exhibited considerably enhanced dyes degradation (CY, 95.12% and EY, 97.82% in 18 min), antibiotics degradation (TC, 96.45% and CIP, 98.01% in 21 min), and nitroaromatics reduction (4-NP, 88.12% and 4-NA, 92.45% in 15 min). The Er-AgNPs have showed significant antibacterial activity on multi drug resistance bacteria. The synthesized Er-AgNPs exhibited strong antioxidant activities for the DPPH assay. Remarkable anti-diabetic (α-glucosidase, α-amylase, and HbA1C) activities were noticed for biosynthesized Er-AgNPs. This is the first report on the biosynthesis of AgNPs using seeds extract of Embelia robusta. • Eco-friendly synthesis of AgNPs were carried out using Embelia robusta seeds extract. • The synthesized Er-AgNPs were found to be fcc structure and average diameter is 8±2 nm. • Biosynthesized Er-AgNPs exhibited excellent catalytic activity for the degradation of dyes, antibiotics, and nitrocompounds reduction at low NaBH 4 content. • Biogenic Er-AgNPs showed good antibacterial, antidiabetic and antioxidant activities. • Er-AgNPs were developed as a four-in-one platform for the environmental remediation of waste water treatment and biological applications.