Abstract
Eclipta prostrata has been long used by humans as traditional medicine and hair fertilizer. This study aims to explain the relationship between utilization and bioactivity of E. prostrata. The method used is a literature review of articles published online on Google Scholar using the keywords E. prostrata, uses E. prostrata, and bioactivity of E. prostrata. Ethnobotanically, E. prostrata is used to treat liver disorders, liver tonic, respiratory disorders (asthma, cough), hepatitis, snake venom poisoning, and gastritis. In the field of beauty E. prostrata is used to nourish hair and treat baldness. The E. prostrata has bioactivity to treat neurodegeneration, asthma, anti-cancer, overcoming baldness, anti-diabetes mellitus, anti-oxidant, anti-inflammatory, anti-microbial, hepatoprotective, anti-osteoporosis, and anti-hypercholesterolemia. The bioactivity of E. prostrata is related to the content of its secondary metabolite compounds. Echinocystic acid and ecclalbasaponin II from E. prostrata are associated with anti-cancer activity.
Highlights
Eclipta prostrata is a species belonging Euphorbiaceae has been long used by various local communities in the world and Indonesia as traditional medicine and to beauty treatments [1,2]
The bioactivity of E. prostrata is related to the content of its secondary metabolite compounds
Echinocystic acid and ecclalbasaponin II from E. prostrata are associated with anti-cancer activity
Summary
Eclipta prostrata is a species belonging Euphorbiaceae has been long used by various local communities in the world and Indonesia as traditional medicine and to beauty treatments [1,2]. This plant is easy and can be found in various landscapes such as yards, roadsides, rice fields, gardens and neglected lands and its considered a weed. Eclipta prostrata has been written in the Indian traditional system medicine such as ayurvedic to treat liver disease and as a liver tonic [2], while in Brazil it is used to treat asthma, respiratory system disorders [3]. Lee et al [6] stated that E. prostrata has been commercialized for the prevention or treatment of hair loss has been commercialized
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