Eclipta alba Derived Phytochemicals against Jaundice

Bhagyeswari Behera,Mukesh Kumar Biswal,Sanchayita Nayak,Srimay Pradhan,Sutapa Mohanty,Ushasree Mandal

doi:10.9734/jpri/2020/v32i730520

Abstract

Phytochemicals otherwise known as secondary metabolites means the small organic molecules that are not essential for growth, development and reproduction but can protect from various diseases. Infact these phytochemicals are the key source of medicine. Secondary metabolites from Eclipta alba plant extract are traditionally used to cure Jaundice which is caused by Leptospira interrogans. The curative property of Eclipta alba against Leptospira interrogans was proved by molecular docking method in “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” recommended that pentadecan, heptadecane, 6,10,14-trimethyl-2-petadecanone can successfully deactivate the thioredoxin-disulfide reductase enzyme thereby disrupting the cellular function as well as the lifecycle of causative organism.

Highlights

IntroductionPeople rely on the nature so we can say medicine is the nature’ best gift we ever know [1]
2.2 MethodologyFor herbal medicine, people rely on the nature so we can say medicine is the nature’ best gift we ever know [1]
Published works showed that Eclipta albacontains6,10,14trimethyl-2-pentadecanone, 7,11-Dimethyl-3methylene-1,6Z,10-dodecatriene, Echinocystiacid, Heptadecane, Octa-9-enoicacidPentadecaneetc.It has already been established that Ecliptaalba belonging to Asteraceae family has potential to help controlling jaundice

Summary

Introduction

People rely on the nature so we can say medicine is the nature’ best gift we ever know [1]. The medicinal properties of the plant are due to the phytochemicals present in it. These phytochemicals can be found in every part of the plant like in roots, stem, leaves, seed and flower etc. One plant can contain a large number of phytoconstituents and because of the defensive mechanism of these phytoconstituent it can be used against various diseases which are mainly caused by microorganisms [2]. From the prehistoric period people have been depending on herbal medicines for their different alignment. A day these medicinal plants are again playing the key role in pharmaceutical sectors [3]

Methods

Results

Conclusion