Abstract
Objective: To evaluate and analyze the echocardiographic changes in end stage renal disease patients on maintenance hemodialysis. Material and methods: End stage renal disease (ESRD) patients on maintenance hemodialysis for at least 3 months were included in the study. We performed M-mode echocardiography in 35 ESRD patients during interdialytic period usually after 18 hours, without obvious clinical evidence of coronary artery disease, valvular heart disease, congenital heart disease and pericardial effusion. Results: Echocardiography revealed LV dilation and diastolic dysfunction in 18 (51.2%), left ventricular hypertrophy (LVH) in 17 (48%), systolic dysfunction and pericardial effusion in 10 (28.57%) and 6 (17.14%) patients respectively. RWMA was present in 8.5% and valvular calcification was not seen in our patient group. In sub-group of patients with Hb<10 gm%, LVH was present in 71.42% (15) vs 14.28% (2) in patient group with Hb ≥ 10 gm% (p=0.002). Hypertensive patient population also had higher prevalence of LVH (51.85%)] and systolic dysfunction and RWMA was absent in normotensive group. Conclusion: LV diastolic dysfunction and hypertrophy were most common echocardiographic findings. There was statistically significant correlation between anemia and presence of LVH and positive correlation between presence of hypertension and LVH.
Highlights
Chronic Kidney Disease (CKD) is a major public health problem worldwide with increase in incidence and prevalence
CKD is risk factor for cardiovascular event and complications increases as CKD progress to end stage renal disease (ESRD) [3]
In this study we evaluated the cardiovascular abnormalities by performing 2-D echocardiography in CKD patients on maintenance hemodialysis (MHD)
Summary
Chronic Kidney Disease (CKD) is a major public health problem worldwide with increase in incidence and prevalence. G protein coupled and Ca2+ dependent kinases are responsible for control of blood pressure [1]. CKD is risk factor for cardiovascular event and complications increases as CKD progress to end stage renal disease (ESRD) [3]. One of the major structural cardiac anomalies in patients with CKD is left ventricular hypertrophy (LVH) and is associated with increase the risk for cardiac ischemia, congestive heart failure, as well as a very strong independent predictor of cardiovascular mortality [4]. Majority patients with CKD die due to cardiovascular events before reaching ESRD due to both traditional and nontraditional risk factors [5]. Whether CV events differ in patients with and without CKD is poorly defined and whether differences in cardiovascular disease in CKD patients suggest preventive or therapeutic strategies unique to this population is unclear
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
