Abstract

Echocardiographic Assessment of Cardiac Complications in Anorexia Nervosa: Correlation with the Disease Severity and the Role of Global Longitudinal Strain

Highlights

  • Anorexia Nervosa (AN) is a psychiatric disorder with devastating physical consequences

  • The average values of weight and Body mass index (BMI) were 39.8±7.2 kg and 15±2.1 kg/m2, respectively. 20 (51.3%) patients were affected by non-extreme AN and 19 (48.7%) patients by extreme AN

  • The major findings of our investigation were: a) LV remodeling, pericardial effusion (PE) and mitral valve prolapse (MVP) correlated with the severity of the disease, on the contrary ECG abnormalities and echocardiographic parameters of LV systolic function did not

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Summary

Introduction

Anorexia Nervosa (AN) is a psychiatric disorder with devastating physical consequences. It is the most frequent eating disorders (ED), mainly affecting young women (10:1 female-male ratio). The incidence of AN has been reported to be 270 to 100.000 person-years in adolescents, it is often underestimated [1]. Its prevalence varies between 0.9% and 3% in women and between 0.16% and 0.3% in men [2]. AN has the high est mortality rate of any psychiatric disorder, with 5.1 deaths per 1000 person years [3]. According to the DSM-5 criteria [4], the diagnosis of AN requires the presence of all the following criteria: a) Persistent restriction of energy intake leading to significantly low body weight;

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