Abstract
In 1966 ECHO virus type 33 was prevalent in the Netherlands. This virus was the cause of an epidemic of aseptic meningitis. The virus was isolated from feces, throat swabs or cerebrospinal fluid of 120 patients. In 73% of 74 patients serologically examined, a significant increase of ECHO 33 neutralizing antibody titer was demonstrated. Meningitis was the main clinical manifestation in 84% of the virus positive cases. The GaBi strain of diploid human embryonic lung fibroblasts was much more sensitive to this virus than cynomolgus monkey kidney cells. Out of 45 specimens tested in both cell systems 43 were positive in GaBi cells whereas only 24 isolates were obtained in monkey kidney cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
