Abstract
Echinococcus multilocularis is a cestode that causes human alveolar echinococcosis, a lethal zoonosis of public health concern in central Asia and western China. In the present study, one of 42 Eastern mole voles (Ellobius tancrei) caught in Sary Mogol (Alay valley, southern Kyrgyzstan) presented liver lesions with E. multilocularis from which the EmsB target was amplified. The Asian profile obtained was almost identical to one amplified from domestic dog faeces collected in a nearby village. This observation adds additional information to the potential role of E. tancrei in the transmission of E. multilocularis, and to the known distribution range of E. multilocularis (Asian strain) in central Asia.
Highlights
The taeniid cestode Echinococcus multilocularis is the causative agent of human alveolar echinococcosis (AE), a potentially lethal helminthic zoonosis (Eckert & Deplazes, 2004)
AE is a rare disease within the distribution range of the parasite, several endemic areas have been reported in North America, Europe and Asia (Vuitton et al, 2003)
One mutation was observed in the referenced sequence in both the forward and reverse sequences, in comparison to the other sequences referenced in the GenBank database for the E. tancrei sample and the dog faeces extract
Summary
The taeniid cestode Echinococcus multilocularis is the causative agent of human alveolar echinococcosis (AE), a potentially lethal helminthic zoonosis (Eckert & Deplazes, 2004). AE is a rare disease within the distribution range of the parasite, several endemic areas have been reported in North America, Europe and Asia (Vuitton et al, 2003). Echinococcus multilocularis has a complex life cycle that involves carnivores (principally foxes) as definitive hosts, and cricetid rodents (e.g. Microtus spp.) or lagomorphs (e.g. Ochotona spp.) as intermediate hosts. Distinct European, Asian and North American genotypes have been described (Bretagne et al, 1996; Bart et al, 2006) and the geographical location of the transitional zone between Asian and European genotypes, somewhere between eastern Europe and western China, is currently unknown. A tandemly repeated microsatellite, EmsB, has been used to describe the relative diversity
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