Abstract

Anorexia nervosa (AN) and bulimia nervosa (BN) are disorders that tend to have their onset in adolescence and occur more frequently in females. These disorders are characterized by restricted and/or binge eating, a relentless pursuit of thinness, and obsessive fears of becoming fat. In addition, AN and BN are often associated with perfectionism, anxiety, depression, and obsessional traits. Although these disorders are often thought to be caused by psychosocial factors, studies show substantial genetic and neurobiological etiological influences. Whereas BN often responds to psychological and pharmacological treatments, AN remains more difficult to treat. Consequently, AN often has a chronic and relapsing course and substantial morbidity and mortality.

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