EasyNanopore: A Ready-to-Use Processing Software for Translocation Events in Nanopore Translocation Experiments

Abstract

We developed EasyNanopore which is a ready-to-use software to select the events of a nanopore molecular translocation experiment. The software is released as an executable file with a graphical user interface and provides several versions suitable for different operating systems without installing any running environment to execute it. We use the adaptive threshold which adapts to the low-frequency variation of the baseline to detect events and uses a multiprocess method to accelerate the process of event detection. After the event is identified, its duration and amplitude information will be extracted and a resulting txt file will be generated for further analysis. Our software runs fast and can effectively extract the data from data of large-scale nanopore molecular translocation experiments.