Early systemic lupus erythematos: onset with thrombosis

Abstract

Systemic lupus erythematosus (SLE) is a global pathology that can affect people of any age, with an average age of onset between 15 and 44 years. The female/male ratio is 13:1, while in children and the elderly it is only 2:1 [2, 5]. SLE can affect any organ and presents a wide spectrum of clinical and immunological manifestations, being one of the conditions with the highest mortality rates among systemic diseases [10]. This article presents the clinical case of patient X, aged 19 years, with subacute SLE, with involvement of the skin, vessels, mucous membranes, kidneys, muscles, hematopoietic system, immune system and secondary seronegative antiphospholipid syndrome. The diagnosis was established based on clinical and immunological SLICC criteria, laboratory tests, ECG, EcoCG, chest X-ray, ultrasonography of internal organs, Doppler ultrasonography of lower limb vessels and brain MRI. Against the background of immunosuppressive, anticoagulant, antiplatelet treatment, the patient’s condition improved and she was discharged with the recommendation to continue the basic and symptomatic treatment.