Early diagnosis of Parkinson disorder based on spiral drawing image modalities using hybrid transfer learning architecture

Abstract

The Spiral Drawing Test (SDT) has become a prominent clinical marker for the early diagnosis of Parkinson’s Disorder (PD) by capturing tremor symptoms. The integration of AI algorithms into a PD diagnosis system has proven to be a breakthrough objective assessment that aids professionals in decision-making. However, there is a need for improvisation of the workflow architectures of AI models to optimize the diagnosis system by reducing the misdiagnosis rate. The proposed system presents PD prediction using a Spiral Drawing Test (SDT) image modality integrated with an Artificial Intelligence (AI) algorithm. The proposed study presents three hybrid workflow architectures formed by integrating three core layers: a data augmentation layer, Transfer Layer (TL)-based feature extraction layer, and Deep Learning (DL)-based classification layer. The results were analyzed by conducting 18 experiments based on the hyperparameter values and workflow architectures. The highest accuracy obtained by the proposed study is 98% for Hybrid Workflow Architecture II.