CORR Synthesis: When Should the Orthopaedic Surgeon Use Artificial Intelligence, Machine Learning, and Deep Learning?
CORR Synthesis: When Should the Orthopaedic Surgeon Use Artificial Intelligence, Machine Learning, and Deep Learning?
1314
- 10.1016/s2589-7500(19)30123-2
- Sep 25, 2019
- The Lancet Digital Health
14
- 10.1097/corr.0000000000001466
- Aug 26, 2020
- Clinical Orthopaedics & Related Research
92
- 10.1016/j.arth.2019.05.034
- Jun 20, 2019
- The Journal of Arthroplasty
506
- 10.1016/j.arth.2018.02.067
- Feb 27, 2018
- The Journal of Arthroplasty
68
- 10.1016/j.spinee.2019.09.007
- Sep 13, 2019
- The Spine Journal
124
- 10.1016/j.arth.2018.12.030
- Dec 27, 2018
- The Journal of Arthroplasty
14
- 10.5435/jaaos-d-19-00688
- May 15, 2020
- Journal of the American Academy of Orthopaedic Surgeons
30
- 10.1016/j.arth.2020.04.059
- Apr 25, 2020
- The Journal of Arthroplasty
133
- 10.1001/jamanetworkopen.2019.6700
- Jul 3, 2019
- JAMA Network Open
42
- 10.1007/s11548-012-0796-0
- Nov 20, 2012
- International Journal of Computer Assisted Radiology and Surgery
- Research Article
1
- 10.3389/fsurg.2024.1329085
- Oct 15, 2024
- Frontiers in surgery
This study presents the development and validation of a Deep Learning Convolutional Neural Network (CNN) model for estimating acetabular version (AV) from native hip plain radiographs. Utilizing a dataset comprising 300 participants with unrelated pelvic complaints, the CNN model was trained and evaluated against CT-Scans, considered the gold standard, using a 5-fold cross-validation. Notably, the CNN model exhibited a robust performance, demonstrating a strong Pearson correlation with CT-Scans (right hip: r = 0.70, p < 0.001; left hip: r = 0.71, p < 0.001) and achieving a mean absolute error of 2.95°. Remarkably, over 83% of predictions yielded errors ≤5°, highlighting the model's high precision in AV estimation. The model holds promise in preoperative planning for hip arthroplasty, potentially reducing complications like recurrent dislocation and component wear. Future directions include further refinement of the CNN model, with ongoing investigations aimed at enhancing preoperative planning potential and ensuring comprehensive assessment across diverse patient populations, particularly in diseased cases. Additionally, future research could explore the model's potential value in scenarios necessitating minimized ionizing radiation exposure, such as post-operative evaluations.
- Supplementary Content
21
- 10.1530/eor-23-0083
- Aug 1, 2023
- EFORT Open Reviews
Artificial intelligence (AI) is increasingly being utilized in orthopedics practice.Ethical concerns have arisen alongside marked improvements and widespread utilization of AI.Patient privacy, consent, data protection, cybersecurity, data safety and monitoring, bias, and accountability are some of the ethical concerns.
- Research Article
6
- 10.29400/tjgeri.2023.362
- Jan 1, 2023
- Turkish journal of Geriatrics
The increasing elderly population globally presents challenges in geriatric healthcare, including better resources, unmet healthcare needs, and sustainability of health and social security systems. Artificial intelligence (AI) is being used to address these challenges, with studies focusing on socially assistive robots, humanoid robots, and robotic pets in elderly care. This review aims to provide a comprehensive overview of the roles of artificial intelligence (AI) technologies in elderly healthcare by identifying the potential benefits and challenges in geriatric healthcare services. AI technologies can potentially improve care and health outcomes for older adults, promote healthy aging, and alleviate the burden on the healthcare system. Moreover, AI systems can assist healthcare providers in assessing potential drug interactions, identifying medication errors, and optimizing medication regimens to minimize side effects and enhance overall patient safety. In addition, AI-supported robots can provide caregivers personalized and efficient care while providing rehabilitation and mobility support for the elderly. Collaboration between healthcare professionals and artificial intelligence holds significant potential to facilitate more effective delivery of care, improve patient outcomes, and optimize health resources for the increasingly aging population. Keywords: Aging; Geriatrics; Artificial Intelligence; Healthcare.
- Research Article
4
- 10.1016/j.arthro.2024.12.011
- Apr 1, 2025
- Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Ethical Application of Generative Artificial Intelligence in Medicine.
- Research Article
19
- 10.1016/j.artmed.2024.102935
- Jul 25, 2024
- Artificial Intelligence In Medicine
Deep learning (DL) in orthopaedics has gained significant attention in recent years. Previous studies have shown that DL can be applied to a wide variety of orthopaedic tasks, including fracture detection, bone tumour diagnosis, implant recognition, and evaluation of osteoarthritis severity. The utilisation of DL is expected to increase, owing to its ability to present accurate diagnoses more efficiently than traditional methods in many scenarios. This reduces the time and cost of diagnosis for patients and orthopaedic surgeons. To our knowledge, no exclusive study has comprehensively reviewed all aspects of DL currently used in orthopaedic practice. This review addresses this knowledge gap using articles from Science Direct, Scopus, IEEE Xplore, and Web of Science between 2017 and 2023. The authors begin with the motivation for using DL in orthopaedics, including its ability to enhance diagnosis and treatment planning. The review then covers various applications of DL in orthopaedics, including fracture detection, detection of supraspinatus tears using MRI, osteoarthritis, prediction of types of arthroplasty implants, bone age assessment, and detection of joint-specific soft tissue disease. We also examine the challenges for implementing DL in orthopaedics, including the scarcity of data to train DL and the lack of interpretability, as well as possible solutions to these common pitfalls. Our work highlights the requirements to achieve trustworthiness in the outcomes generated by DL, including the need for accuracy, explainability, and fairness in the DL models. We pay particular attention to fusion techniques as one of the ways to increase trustworthiness, which have also been used to address the common multimodality in orthopaedics. Finally, we have reviewed the approval requirements set forth by the US Food and Drug Administration to enable the use of DL applications. As such, we aim to have this review function as a guide for researchers to develop a reliable DL application for orthopaedic tasks from scratch for use in the market.
- Research Article
- 10.1016/j.recot.2025.08.004
- Aug 1, 2025
- Revista Española de Cirugía Ortopédica y Traumatología
Fiabilidad de la inteligencia artificial (ChatGPT) en el diagnóstico y clasificación de las fracturas de meseta tibial
- Research Article
1
- 10.3389/fneph.2023.1266967
- Oct 26, 2023
- Frontiers in nephrology
The COVID-19 pandemic resulted in an unprecedented burden on intensive care units (ICUs). With increased demands and limited supply, critical care resources, including dialysis machines, became scarce, leading to the undertaking of value-based cost-effectiveness analyses and the rationing of resources to deliver patient care of the highest quality. A high proportion of COVID-19 patients admitted to the ICU required dialysis, resulting in a major burden on resources such as dialysis machines, nursing staff, technicians, and consumables such as dialysis filters and solutions and anticoagulation medications. Artificial intelligence (AI)-based big data analytics are now being utilized in multiple data-driven healthcare services, including the optimization of healthcare system utilization. Numerous factors can impact dialysis resource allocation to critically ill patients, especially during public health emergencies, but currently, resource allocation is determined using a small number of traditional factors. Smart analytics that take into account all the relevant healthcare information in the hospital system and patient outcomes can lead to improved resource allocation, cost-effectiveness, and quality of care. In this review, we discuss dialysis resource utilization in critical care, the impact of the COVID-19 pandemic, and how AI can improve resource utilization in future public health emergencies. Research in this area should be an important priority.
- Research Article
4
- 10.2196/42788
- Oct 20, 2023
- JMIR Formative Research
BackgroundTotal hip replacement (THR) is considered the gold standard of treatment for refractory degenerative hip disorders. Identifying patients who should receive THR in the short term is important. Some conservative treatments, such as intra-articular injection administered a few months before THR, may result in higher odds of arthroplasty infection. Delayed THR after functional deterioration may result in poorer outcomes and longer waiting times for those who have been flagged as needing THR. Deep learning (DL) in medical imaging applications has recently obtained significant breakthroughs. However, the use of DL in practical wayfinding, such as short-term THR prediction, is still lacking.ObjectiveIn this study, we will propose a DL-based assistant system for patients with pelvic radiographs to identify the need for THR within 3 months.MethodsWe developed a convolutional neural network–based DL algorithm to analyze pelvic radiographs, predict the hip region of interest (ROI), and determine whether or not THR is required. The data set was collected from August 2008 to December 2017. The images included 3013 surgical hip ROIs that had undergone THR and 1630 nonsurgical hip ROIs. The images were split, using split-sample validation, into training (n=3903, 80%), validation (n=476, 10%), and testing (n=475, 10%) sets to evaluate the algorithm performance.ResultsThe algorithm, called SurgHipNet, yielded an area under the receiver operating characteristic curve of 0.994 (95% CI 0.990-0.998). The accuracy, sensitivity, specificity, and F1-score of the model were 0.977, 0.920, 0932, and 0.944, respectively.ConclusionsThe proposed approach has demonstrated that SurgHipNet shows the ability and potential to provide efficient support in clinical decision-making; it can assist physicians in promptly determining the optimal timing for THR.
- Research Article
- 10.1097/corr.0000000000002820
- Sep 4, 2023
- Clinical orthopaedics and related research
CORR Synthesis: Can Decision Tree Learning Advance Orthopaedic Surgery Research?
- Research Article
11
- 10.2106/jbjs.rvw.22.00086
- Oct 1, 2022
- JBJS Reviews
With increasing computing power, artificial intelligence (AI) has gained traction in all aspects of health care delivery. Orthopaedics is no exception because the influence of AI technology has become intricately linked with its advancement as evidenced by increasing interest and research. This review is written for the orthopaedic surgeon to develop a better understanding of the main clinical applications and potential benefits of AI within their day-to-day practice. A brief and easy-to-understand foundation for what AI is and the different terminology used within the literature is first provided, followed by a summary of the newest research on AI applications demonstrating increased accuracy and convenience in risk stratification, clinical decision-making support, and robotically assisted surgery.
- Research Article
9
- 10.1111/ajo.13661
- Apr 1, 2023
- Australian and New Zealand Journal of Obstetrics and Gynaecology
Artificial intelligence: Friend or foe?
- Research Article
6
- 10.1111/resp.14061
- Apr 14, 2021
- Respirology
Artificial intelligence in COPD: Possible applications and future prospects.
- Research Article
- 10.5001/omj.2024.79
- May 30, 2024
- Oman medical journal
Chronic liver disease and cirrhosis are persistent global health threats, ranking among the top causes of death. Despite medical advancements, their mortality rates have remained stagnant for decades. Existing scoring systems such as Child-Turcotte-Pugh and Mayo End-Stage Liver Disease have limitations, prompting the exploration of more accurate predictive methods using artificial intelligence and machine learning (ML). We retrospectively reviewed the data of all adult patients with acute decompensated liver cirrhosis admitted to a tertiary hospital during 2015-2021. The dataset underwent preprocessing to handle missing values and standardize continuous features. Traditional ML and deep learning algorithms were applied to build a 28-day mortality prediction model. The subjects were 173 cirrhosis patients, whose medical records were examined. We developed and evaluated multiple models for 28-day mortality prediction. Among traditional ML algorithms, logistic regression outperformed was achieving an accuracy of 82.9%, precision of 55.6%, recall of 71.4%, and an F1-score of 0.625. Naive Bayes and Random Forest models also performed well, both achieving the same accuracy (82.9%) and precision (54.5%). The deep learning models (multilayer artificial neural network, recurrent neural network, and Long Short-Term Memory) exhibited mixed results, with the multilayer artificial neural network achieving an accuracy of 74.3% but lower precision and recall. The feature importance analysis identified key predictability contributors, including admission in the intensive care unit (importance: 0.112), use of mechanical ventilation (importance: 0.095), and mean arterial pressure (importance: 0.073). Our study demonstrates the potential of ML in predicting 28-day mortality following hospitalization with acute decompensation of liver cirrhosis. Logistic Regression, Naive Bayes, and Random Forest models proved effective, while deep learning models exhibited variable performance. These models can serve as useful tools for risk stratification and timely intervention. Implementing these models in clinical practice has the potential to improve patient outcomes and resource allocation.
- Research Article
2
- 10.21271/zjpas.34.2.3
- Apr 12, 2022
- ZANCO JOURNAL OF PURE AND APPLIED SCIENCES
Comprehensive Study for Breast Cancer Using Deep Learning and Traditional Machine Learning
- Research Article
- 10.26442/18151434.2025.2.203225
- Jul 17, 2025
- Journal of Modern Oncology
The review presents a comprehensive analysis of the latest advances in machine learning (ML), artificial neural networks (ANN), and deep learning (DL) in urologic oncology. As part of the study, the Russian and foreign scientific literature was ranked based on PubMed, MEDLINE, E-library, CYBERLENINKA, etc. The data related to the use of ML, ANN, and DL in the diagnosis and treatment of prostate cancer (PCa), bladder cancer (BC), testicular cancer, and kidney cancer was collected. Most often, ANN and ML in PCa were used for early diagnosis, prognosis, and personalized systemic treatment strategy development. ANN and DL models were trained with clinical parameters, NGS-sequencing results, Gleason scores, and digitized radiological, and histological images. Radiomics was also used to diagnose PCa, followed by analysis of special image texture features on a digital slide. In metastatic castration-resistant PCa, artificial intelligence (AI) algorithms were used to predict the response to docetaxel treatment. The prospects of using AI for tumor imaging during radical prostatectomy and when performing robot-assisted kidney resection were also addressed. A diagnostic approach for testicular malignancies based on computed tomography data is proposed using ML. Neuro-fuzzy modeling and ANN were used to diagnose BC. The algorithms were based on molecular biomarkers, including gene expression and methylation. The ML method based on images of cells obtained from urine samples of patients diagnosed with BC showed a diagnostic accuracy of 94%. DL in BC was used for accurate tumor typing based on their response to chemotherapy. Based on the results of deep machine learning, the molecular subtype of BC samples was predicted using histological examination. ML and DL algorithms for diagnosis, differential diagnosis, and prediction of recurrence and survival in kidney cancer were trained on CT texture analysis, genetic mutations, and Fuhrman nuclear grade. In addition to diagnosis, AI is used to optimize the treatment strategy for kidney cancer. In all cases, the ML, ANN, and DL algorithms improved the accuracy of diagnosis, survival assessment, and the effectiveness of pharmacological and surgical treatment of urologic malignancies.
- Research Article
3
- 10.1097/sla.0000000000005396
- Jan 25, 2022
- Annals of Surgery
Machine Learning Reimagined: The Promise of Interpretability to Combat Bias.
- Research Article
7
- 10.1371/journal.pone.0278364
- Dec 1, 2022
- PLOS ONE
Next basket recommendation is a critical task in market basket data analysis. It is particularly important in grocery shopping, where grocery lists are an essential part of shopping habits of many customers. In this work, we first present a new grocery Recommender System available on the MyGroceryTour platform. Our online system uses different traditional machine learning (ML) and deep learning (DL) algorithms, and provides recommendations to users in a real-time manner. It aims to help Canadian customers create their personalized intelligent weekly grocery lists based on their individual purchase histories, weekly specials offered in local stores, and product cost and availability information. We perform clustering analysis to partition given customer profiles into four non-overlapping clusters according to their grocery shopping habits. Then, we conduct computational experiments to compare several traditional ML algorithms and our new DL algorithm based on the use of a gated recurrent unit (GRU)-based recurrent neural network (RNN) architecture. Our DL algorithm can be viewed as an extension of DREAM (Dynamic REcurrent bAsket Model) adapted to multi-class (i.e. multi-store) classification, since a given user can purchase recommended products in different grocery stores in which these products are available. Among traditional ML algorithms, the highest average F-score of 0.516 for the considered data set of 831 customers was obtained using Random Forest, whereas our proposed DL algorithm yielded the average F-score of 0.559 for this data set. The main advantage of the presented Recommender System is that our intelligent recommendation is personalized, since a separate traditional ML or DL model is built for each customer considered. Such a personalized approach allows us to outperform the prediction results provided by general state-of-the-art DL models.
- Research Article
31
- 10.1016/j.otsr.2022.103456
- Oct 24, 2022
- Orthopaedics & Traumatology: Surgery & Research
Artificial intelligence and treatment algorithms in spine surgery
- Front Matter
13
- 10.1016/j.bja.2021.03.015
- Apr 24, 2021
- British Journal of Anaesthesia
Perioperative hypotension 2021: a contrarian view
- Research Article
37
- 10.1007/s10661-024-12454-z
- Feb 24, 2024
- Environmental Monitoring and Assessment
Digital image processing has witnessed a significant transformation, owing to the adoption of deep learning (DL) algorithms, which have proven to be vastly superior to conventional methods for crop detection. These DL algorithms have recently found successful applications across various domains, translating input data, such as images of afflicted plants, into valuable insights, like the identification of specific crop diseases. This innovation has spurred the development of cutting-edge techniques for early detection and diagnosis of crop diseases, leveraging tools such as convolutional neural networks (CNN), K-nearest neighbour (KNN), support vector machines (SVM), and artificial neural networks (ANN). This paper offers an all-encompassing exploration of the contemporary literature on methods for diagnosing, categorizing, and gauging the severity of crop diseases. The review examines the performance analysis of the latest machine learning (ML) and DL techniques outlined in these studies. It also scrutinizes the methodologies and datasets and outlines the prevalent recommendations and identified gaps within different research investigations. As a conclusion, the review offers insights into potential solutions and outlines the direction for future research in this field. The review underscores that while most studies have concentrated on traditional ML algorithms and CNN, there has been a noticeable dearth of focus on emerging DL algorithms like capsule neural networks and vision transformers. Furthermore, it sheds light on the fact that several datasets employed for training and evaluating DL models have been tailored to suit specific crop types, emphasizing the pressing need for a comprehensive and expansive image dataset encompassing a wider array of crop varieties. Moreover, the survey draws attention to the prevailing trend where the majority of research endeavours have concentrated on individual plant diseases, ML, or DL algorithms. In light of this, it advocates for the development of a unified framework that harnesses an ensemble of ML and DL algorithms to address the complexities of multiple plant diseases effectively.
- Research Article
86
- 10.1016/j.isci.2020.101515
- Aug 29, 2020
- iScience
SummaryThe recent sale of an artificial intelligence (AI)-generated portrait for $432,000 at Christie's art auction has raised questions about how credit and responsibility should be allocated to individuals involved and how the anthropomorphic perception of the AI system contributed to the artwork's success. Here, we identify natural heterogeneity in the extent to which different people perceive AI as anthropomorphic. We find that differences in the perception of AI anthropomorphicity are associated with different allocations of responsibility to the AI system and credit to different stakeholders involved in art production. We then show that perceptions of AI anthropomorphicity can be manipulated by changing the language used to talk about AI—as a tool versus agent—with consequences for artists and AI practitioners. Our findings shed light on what is at stake when we anthropomorphize AI systems and offer an empirical lens to reason about how to allocate credit and responsibility to human stakeholders.
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10
- 10.1097/tp.0000000000003304
- Aug 18, 2020
- Transplantation
Artificial Intelligence-related Literature in Transplantation: A Practical Guide.
- Discussion
- 10.1111/anae.15022
- Mar 12, 2020
- Anaesthesia
Teaching an old dog new tricks: three-dimensional visual spatialisation of viscoelastic testing and artificial intelligence.
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44
- 10.1002/aps3.11371
- Jun 1, 2020
- Applications in Plant Sciences
Plants meet machines: Prospects in machine learning for plant biology
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- 10.24976/discov.med.202537192.7
- Jan 1, 2025
- Discovery medicine
Acute pancreatitis (AP) is a prevalent pathological condition of abdomen characterized by sudden onset, high incidence and complex progression. Timely assessment of AP severity is crucial for informing intervention decisions so as to delay deterioration and reduce mortality rates. Existing AP-related scoring systems can only assess current condition of patients and utilize only a single type of clinical data, which is of great limitation. Therefore, it is imperative to establish more accurate and data-compatible methods for predicting the severity of AP. The artificial intelligence (AI) algorithm based on artificial neural network (ANN) allow for the adaptive feature extraction for objective task through its internal complex network, instead of the hand-crafted methods commonly used in traditional machine learning (ML) algorithms. In this study, we delve into the final severity classification prediction of newly admitted AP patients, using deep learning (DL) algorithm to develop multi-view models, incorporated with patients' demographic information, vital signs, AP-related laboratory indexes and admission computed tomography (CT) images. The pancreatitis database in the platform of Clinical Data Research Center of Acute Abdominal Surgery at the First Affiliated Hospital of Dalian Medical University was used to gather AP cases. Deep neural network (DNN) and convolutional neural network (CNN) were utilized to construct models. The DNN prediction models with clinical data as input, the CNN prediction models with admission CT as input, and the multi-view models combining the two inputs were respectively established to predict the severity of AP. DL models for AP severity classification based on clinical indexes, imaging data and merged data were constructed. The multi-view model based on merged data offered more accurate prediction of the final severity classification of AP, with an overall accuracy rate of 80.26% (95% confidence interval (CI): 79.58%-80.94%). The constituent accuracy rates for mild acute pancreatitis, moderately severe acute pancreatitis, and severe acute pancreatitis were 91.69% (95% CI: 87.80%-95.57%), 64.90% (95% CI: 58.85%-70.95%), and 75.56% (95% CI: 68.58%-82.53%), respectively. The multi-view models using clinical indexes and imaging data as input outperform single-view models in AP severity prediction.
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