Abstract
Our group recently validated urinary chitinase 3-like protein 1 (UCHI3L1) as novel biomarker for acute kidney injury (AKI) in septic mice [1].
Highlights
Our group recently validated urinary chitinase 3-like protein 1 (UCHI3L1) as novel biomarker for acute kidney injury (AKI) in septic mice [1]
Baseline characteristics showed no differences with the exception of age (70.5 y [IQR: 65.8-78.0] vs. 59.0 [50.0-70.0] for endpoint pos. resp. neg.; P = 0.040)
At ICU admission, the only significant difference was the proportion of patients referred from another department (66.7 vs. 22.3% for endpoint pos. resp. neg.; P = 0.029)
Summary
This ensuing study aimed to investigate whether our preclinical finding could be translated to humans and whether UCHI3L1 performed to the AKI biomarker urinary neutrophil gelatinase-associated lipocalin (UNGAL) [2]
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