Abstract
ESPITE more than half a century of investigation,acute kidney injury (AKI) remains a major healthcareissue in medicine today. Reported to occur in 1–32% of allhospital admissions and 10–90% of intensive care unit ad-missions, the wide variation reflects different criteria used todefineAKI.However,independentofdefinition,adiagnosisof AKI is consistently associated with an increase in bothshort- and long-term morbidity and mortality. Even themildest forms of AKI are independently associated with in-creased early as well as long-term mortality, the risk increas-ing as severity of renal injury increases.
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