Early Clinical Experiences with Terumo’s New Hollow Fiber Membrane Oxygenator: Capiox II

Abstract

Terumo’s Capiox II is a hollow fiber membrane oxygenator with an integrated heat exchanger. This device is available in 1.6 m2, 3.3 m2, 4.3 m2, and 5.4 m2 sizes. Our clinical experiences have been with the 3.3 m2, 4.3 m2, and 5.4 m2 sizes, in over 150 open-heart patients. The 3.3 m2 was sized to patients up to 60 kg. The 5.4 m2 was used in all patients >60 kg. Both normothermic and hypothermic (24°-30° bladder) perfusions were performed. The heat exchanger was efficient and demonstrated structural integrity. On bypass, patient vital signs, gas and blood flows, arterial and venous blood gases and blood chemistries were monitored. Arterial saturations were 100%. Venous saturations were at least 65%. No acid-base problems were encountered. Initially, 100% oxygen was used. Later a gas blender using O2 and compressed air was utilized. Our experience concludes that the Capiox II is a safe, efficient onepump membrane oxygenator with integral heat exchanger. It is easy to set up and recirculate, delivering satisfactory oxygen transfer rates with a blended gas to blood flow ratio (≤1:1).