Abstract
Background: Primary knee Osteoarthritis (OA) is the commonest articular disease in middle age and elderly people. Primary total knee replacement (TKR) is a known world-wide standard and definitive treatment of primary knee OA following failed adequate non-operative management. It is of clinical importance to assess the clinical and functional outcome of TKR to prognosticate the severity of primary knee OA. The new (2011) knee society scoring system (nKSS) is both surgeons and patients’ assessment tool for the treatment outcome of TKR. Study Design: Prospective interventional analytical study. Aim and Objective: The aim of the study was to determine early clinical and functional outcome of primary total knee replacement in patients with primary knee osteoarthritis using nKSS. The objectives were: 1) To determine the pre-operative nKSS and post operative nKSS; 2) To determine relationships between pre-operative nKSS and post operative nKSS at 6 weeks, 3, 6, 9 and 12 months; 3) To determine the complication rates in patients undergoing primary TKR in the study centre. Methods: A prospective interventional study of 59 patients aged 51 to 70 years who had 67 Total Knee Replacements (TKRs) participated in the study between November 2015 to June 2018 at National Orthopaedics Hospital, Lagos, Nigeria. Patients’ sociodemographic data, pre-operative and post-operative nKSS system were recorded at 6 weeks, 3, 6, 9 and 12 months during follow up. The data were analyzed using Statistical Package for Social Science (SPSS). Results: There were 41 females and 18 males (M:F = 1:2.3). There were total of 67 TKRs with 31 right TKRs, 20 left TKRs and 8 staged bilateral TKRs. The participants’ age ranged from 51 to 70 years with the mean age of 59.5 (±8.5) years. Four patients did not complete the study due to various reasons. The remaining 55 participants completed the study period with progressive improvement of their post-operative nKSS at 6 weeks, 3, 6, 9 and 12 months post-operatively when compared with pre-operative nKSS (P value 0.5). Conclusion: This study revealed improved early clinical and functional outcome of primary total knee replacement in primary knee osteoarthritis using nKSS in all the studied patients. There is no significant negative effect of lower pre-operative nKSS (and its components) on the post-operative nKSS outcome.
Highlights
Primary knee Osteoarthritis (OA) is a pandemic disease of global importance which leads to disability and negatively affects the daily activities of patients [1]
This study revealed improved early clinical and functional outcome of primary total knee replacement in primary knee osteoarthritis using new (2011) Knee Society Score (nKSS) in all the studied patients
The aim of this study was to examine in our practice, early clinical and functional outcome of primary total knee replacement in patients with primary knee osteoarthritis using nKSS while the objectives of this study were: 1) To determine the pre-operative nKSS and post operative nKSS at 6 weeks, 3, 6, 9 and 12 months respectively; 2) To determine relationships between pre-operative nKSS and post operative nKSS at 6 weeks, 3, 6, 9 and 12 months respectively; 3) To determine the complication rates in patients undergoing primary Total knee replacement (TKR) in the study centre
Summary
Primary knee Osteoarthritis (OA) is a pandemic disease of global importance which leads to disability and negatively affects the daily activities of patients [1] It is the commonest articular disease in middle age and elderly people [2] [3]. It is a leading cause of physical and functional disability, cause of socioeconomic burden and expense, including time lost from work, medical care, and disability support to the patient and to the family members and community [1] [4] [5].
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