Abstract
Treatment of dysmenorrhea by the suppression of ovulation with estrogen therapy is reported. 178 cycles of treatment were studied in 30 patients. The correlation of dysmenorrhea and ovulation was studied by endometrial biopsy and basal body temperature (BBT). 82 biopsies and 11 temperature records were obtained from 5 patients. In 50 baseline (untreated) cycle 46 progestational and 4 estrogenic endometriums were seen. Pain was associated with progestational biopsies. Of 32 biopsies taken after treatment 21 were progestational and 11 estrogenic. An ovulatory BBT was also associated with a progestational endometrium and with pain. In 91 cycles treated with less than 25 mg of remarin or less than 20 mg of diesthylstilbestrol (DES) 25.3% were totally relieved. In 53 cycles treated with 25 mg remarin or 20 mg DES 49.1% were totally relieved. In 23 cycles treated with 75 mg and 60 mg respectively 78.3% were totally relieved. All failures were associated with a progestational endometrium. In order to establish the optimal dosage for individual patients it is advisable to follow treatment with endometrial biopsies and BBT. Gross menstrual disturbances were absent during treatment.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call