Abstract
Background: Dysfunctional uterine bleeding (DUB) is a form of abnormal uterine bleeding and it is one of the most common presenting complains in gynecology outpatient department in all age groups.Aim and Objectives: The present study aimed to study the clinical features and various histological patterns of endometrium in DUB and correlating histopathology of endometrium with clinical presentation in clinically diagnosed cases of DUB.Methods: Present study is a descriptive type of study conducted over 111 cases over a period of one year from June 2015- June 2016 in the department of pathology at a tertiary care centreResults: Majority of patients with DUB were in 3rd to 4th decade (40.35%) and were multiparous (93.3%). Of the 111 cases, 51.35% of cases showed histological features associated with DUB. Menorrhagia was the most frequent presenting complaint (56.14%) followed by metrorrhagia in 14.04%. Proliferative phase (50.88%) was the most common endometrial pattern seen with DUB cases in age group from 21-50 years. Endometrial hyperplasia occurred between the age group of 30-50years.Conclusion: Menorrhagia is the most common presenting complaint with proliferative phase endometrium. Age has definite influence on endometrial histology. Histopathology remains the gold standard method of diagnosis of DUB and its types and to exclude the local causes, so as to plan the accurate management in DUB patients. DOI: 10.21276/APALM.1169
Highlights
The normal menstrual cycle consists of length of 21-35 days, the duration of blood flow is 2-7 days and the amount of blood loss is 20-80ml
Abnormal uterine bleeding (AUB) can be further classified into two broad groups first due to organic causes with pathology and the second is the dysfunctional uterine bleeding (DUB) where there is absence of organic disease of the genital tract or according to Novak et al Dysfunctional uterine bleeding (DUB) can be described as AUB from the uterus unassociated with the tumour, inflammation or pregnancy.[2,3]
A total of 622 hysterectomy specimens were received to the deprtment of pathology out of which clinically diagnosed DUB cases with hysterectomy accounted for 17.85% (111 of cases) of the total specimens received
Summary
The normal menstrual cycle consists of length of 21-35 days, the duration of blood flow is 2-7 days and the amount of blood loss is 20-80ml. Abnormal uterine bleeding (AUB) can be further classified into two broad groups first due to organic causes with pathology and the second is the dysfunctional uterine bleeding (DUB) where there is absence of organic disease of the genital tract or according to Novak et al DUB can be described as AUB from the uterus unassociated with the tumour, inflammation or pregnancy.[2,3]. DUB can be classified into primary, secondary and iatrogenic groups. Dysfunctional uterine bleeding (DUB) is the term used to describe abnormal uterine bleeding not associated with organic lesions of uterus[7]. Dysfunctional uterine bleeding (DUB) is a form of abnormal uterine bleeding and it is one of the most common presenting complains in gynecology outpatient department in all age groups
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