Abstract
Aim. To evaluate the heart rate variability (HRV) in patients with ischemic heart disease (IHD) and paroxysmal atrial fibrillation (AF) during atorvastatin therapy. Material and methods . 60 patients with IHD and paroxysmal AF were included in the study. Patients were divided into two groups – control group (basic antiarrhythmic therapy) and second group (basic antiarrhythmic therapy and atorvastatin (Liptonorm, Pharmstandart, Russia) 10mg/day). HRV was compared before and after 3 months of therapy in both groups. Results. Liptonorm significantly improved HRV indices in comparison with basic therapy alone: RMSSD increased on 33% (р <0,02), total power (TP) of spectrum on 28% (р <0,03) and high frequency (HF) component on 53 % (р <0,01). Conclusion. Liptonorm therapy improves autonomic balance in patients with IHD and paroxysmal AF.
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