DYNAMICS OF INCIDENCE RATE AND CAUSES OF THE LATE DIAGNOSIS OF GASTRIC CANCER IN THE ARKHANGELSK REGION IN 2006-2015

Abstract

Gastric cancer (C16) remains one of the most prognostic unfavorable form of malignant neoplasms in Russia, primarily due to its late diagnostics. Aim of this study is to assess the dynamics of the incidence rate of gastric cancer in the Arkhangelsk region in 2006-2015 and to reveal the reasons for its late diagnosis (clinical stage IV). Material end methods. We used the data of population-based cancer registry of the Arkhangelsk region. Binary logistic regression analysis was performed to assess the odds ratios of the late diagnosis of gastric cancer (clinical stage IV) from an array of predictors (gender, place of residence, and the patient’s age at diagnosis). Results. The incidence rate of gastric cancer in the Arkhangelsk region in 2006-2015 was higher than in Russia as a whole (36.0-45.3 cases per 100,000 and 25.9-29.4 cases per 100,000 respectively). Every second (43.9%) new case of this neoplasm was revealed at the clinical stage IV. The proportion of these patients was stable in 2006-2015 (from 40.5% to 48.6%). Errors of primary care doctors in Arkhangelsk region were the main reason of the late diagnosis of gastric cancer (61.9%-73.8%). Every third new case of this neoplasm (26.2%-38.1%) was diagnosed at the clinical stage IV due to the low quality of patients’ self-preservation behavior. Patient’s age was associated with the late diagnosis of gastric cancer: every additional year reduced the odds ratio of the outcome for 2-3%. Conclusion. Obtained results determine the elimination of errors in the diagnostic work of primary care doctors (especially strengthening the readiness to diagnose the neoplasms) as an essential condition for the reduction of gastric cancer mortality in the Arkhangelsk region.