Abstract

This article describes the results of a study of cholesterol metabolism in cows during the transit period. Cows were selected with optimal and increased body fatness during the dry period three weeks before calving. Blood samples were taken twice before calving and twice after calving at regular intervals. In the blood serum, the concentration of cholesterol and its fractions - low-density lipoprotein cholesterol and high-density lipoprotein - was studied, as well as the concentration of β-hydroxybutyric acid on the fifth day after calving. Studies have shown unidirectional dynamics of cholesterol and its fractions during the observation period. Initially, a decrease in all indicators was determined, the minimum values were found during the first week after calving. By the end of the experiment, all cholesterol fractions increased. It was found that in cows with increased body condition during the dry period, the level of LDL cholesterol in the post-calving period was significantly lower by 19.0-25.4% than in cows with optimal body condition. It was also found that in well-fed cows ketogenesis is more active 5 days after calving. Thus, in cows with increased and optimal fatness, the concentration of β- hydroxybutyric acid was 1.63 ± 0.18 and 1.23 ± 0.11 mmol / l, respectively, which may indicate the presence of subclinical ketosis in obese cows.

Highlights

  • In this study, to activate the humoral link of nonspecific resistance of the fish organism, as well as to stimulate growth and development, prevent infectious and invasive diseases, the drug "SmartBiotic" was used, which contains humic acids

  • The research was carried out on the basis of LLC "Lososevo - whitefish nursery" Kingisepsky district, Leningrad region, the village of Velkota, which is the largest nursery in the city of Kingisepp for breeding rainbow trout

  • The first experimental group of young of the year received the drug at a concentration of 0.15%, and the second experimental group - at a dose of 0.25%

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Summary

ДИНАМИКА ФРАКЦИЙ ХОЛЕСТЕРИНА У КОРОВ В ТРАНЗИТНЫЙ ПЕРИОД

Васильева С.В., orcid.org/0000-0002-7324-6250 (ФГБОУ ВО «Санкт-Петербургский государственный университет ветеринарной медицины»). В сыворотке крови исследовали концентрацию холестерина и его фракций – холестерина липопротеинов низкой плотности и липопротеинов высокой плотности, а также концентрацию β-гидроксимасляной кислоты на пятый день после отёла. Что у упитанных коров более активно идёт кетогенез через 5 дней после отёла. Холестерин, образующийся в печени у коров, транспортируется в периферические ткани в составе ЛПНП, а удаляется из клеток в печень для превращения в желчные кислоты – в составе ЛПВП [3, 5, 6]. Предшественником для образования холестерина является ацетил-КоА, который может образовываться у коров непосредственно из ацетата, а также при окислении жирных кислот. Что у коров после отёла довольно резко изменяется обмен веществ за счёт интенсификации лактогенеза, при этом активируется окислительный метаболизм в целом, а также обмен липидов. В задачу наших исследований вошло изучение динамики холестерина и его фракций в течение транзитного периода у коров

МАТЕРИАЛЫ И МЕТОДЫ
РЕЗУЛЬТАТЫ И ОБСУЖДЕНИЕ
Срок после отёла
DYNAMICS OF CHOLESTEROL FRACTIONS IN COWS DURING THE TRANSIT PERIOD
КОШКИ ДОМАШНЕЙ
МАТЕРИАЛ И МЕТОДЫ
Full Text
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