Abstract

The dynamics of biochemical parameters (lipid peroxidation, medium molecular peptides, prostaglandins) blood levels after periodontal tissues surgery of 24 dogs with spontaneous periodontitis has been studied. Animals were divided into groups with normal, hyper- and hyporeactivity of the body. It has been revealed that the changes of the studied biochemical parameters during normoreactivity of the organism are mutually correlated, which provides synchronization of necrotic and reparative processes in the healing of mucosal wounds after patch surgery in cases of spontaneous periodontitis. When hyperreactivity of organism is observed, the changes of indicators of lipid peroxidation, medium molecular peptides and prostaglandins promote strengthening of necrotic processes, and in cases of hyporeactivity they boost their slowing down that in both cases leads to delay of reparation in healing of an artificial mucous-bone wound. Keywords: spontaneous periodontitis, reactivity of the organism, wound healing, biochemical parameters.

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