Abstract

Background: This cross sectional study was carried out to observe Doppler wave form in subjects with preeclampsia enrolling 40 subjects with preeclampsia, in the Department of Radiology and Imaging, Dhaka Medical College Hospital, Dhaka, over a period of six months from 20th May 2012. A total number of 40 normal pregnancies were also included for comparison.
 Methods: Objective of the study was to observe Doppler wave form in subjects with preeclampsia. While specific object is To see PSV, EDV, RI, PI in different groups of study subjects from 24th to 37th weeks and find out significant difference of different Doppler indices in between two groups (i.e.,to calculate the proportion of subjects having early diastolic notch in two groups).
 Results: Majority (35% in normal and 37.5% in preeclampsia) of the respondents were found in the age group of 21-30 years. Unpaired t-test revealed no significant difference between mean age between two groups. Among normal group, mean±SD PSV, EDV, PI and RI were 43.94±15.41 cm/sec and 15.51 (±4.93) cm/sec, 1.12±0.0846 and 0.571 (±0.058) respectively. Mean PSV, EDV, PI and RI were 83.19±18.44 cm/sec, 11.86±5.19 cm/sec, 2.497±0.369 and 0.8255±0.087 in preeclampsia group. There was statistically significant (By unpaired t-test) difference in mean Doppler indices between these two groups. It was observed that early diastolic notch was found in 90% subjects with preeclampsia. Early diastolic notch was observed in Doppler wave form in 5% subject with normal pregnancy. Chi-square test showed that there was statistically significant difference in presence of early diastolic notch between normal subjects and subjects with preeclampsia.
 Conclusion: It may be concluded that doppler indices with presence of early diastolic notch are reliable indicators for early detection of preeclampsia.
 Bangladesh Med Res Counc Bull 2019; 45: 34-40

Highlights

  • Among the various imaging tools in the Department of Radiology and Imaging, use of duplex colour doppler sonography is gaining increasing popularity for assessment of blood vessels in various disease processes around the world

  • Majority (35% in normal and 37.5% in preeclampsia) of the respondents were found in the age group of 21-30 years

  • It was observed that early diastolic notch was found in 90% subjects with preeclampsia

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Summary

Introduction

Among the various imaging tools in the Department of Radiology and Imaging, use of duplex colour doppler sonography is gaining increasing popularity for assessment of blood vessels in various disease processes around the world. The past 20 years have seen an enormous growth in both technical aspects of doppler ultrasound and its application in obstetric and foetal medicine. Doppler ultrasound has important screening and diagnostic capabilities.[1,2,3] In addition, doppler ultrasound has an important contribution to the surveillance of foetus compromised by intra uterine growth retardation (IUGR) and to assess foetal structural abnormalities and complex disease. Screening for preeclampsia may allow vigilant antenatal surveillance and appropriate timing of foetal delivery in order to avoid serious sequelae. Doppler ultrasound has important screening and diagnostic capabilities for screening preeclampsia

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