Abstract
Duodenal Contents Reflux can Induce Esophageal Squamous Cell Carcinoma as Well as Adenocarcinoma
Highlights
Esophageal carcinoma is the eighth most common cancer, and the sixth most common cause of cancer-related deaths worldwide [1]
Esophageal cancer can arise as esophageal squamous cell carcinoma (ESCC) or esophageal adenocarcinoma (EAC), which have distinct etiological and pathological characteristics
gastroesophageal reflux disease (GERD) has not generally been considered to be a risk factor for ESCC, we discuss the potential relationship between ESCC and the duodenal contents based on recent contributions to the literature and our own experimental results in animal models
Summary
Duodenal Contents Reflux can Induce Esophageal Squamous Cell Carcinoma as Well as Adenocarcinoma. List of abbreviations: ESCC-Esophageal Squamous Cell Carcinoma; EAC-Esophageal Adenocarcinoma; GERD-Gastroesophageal Reflux Disease
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