Abstract
In this study, we constructed a pH/laccase dual responsive drug delivery system, denoted as IMI@(CMCS+SL)n, capable of modulating wall thickness and drug release via the layer-by-layer deposition of carboxymethyl chitosan (CMCS) and sodium lignosulfonate (SL). The IMI@(CMCS+SL)n microcapsules was characterized by Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), (energy-dispersive X-ray spectroscopy) EDS, X-ray photoelectron spectroscopy (XPS), and dynamic light scattering techniques (DLS) analysis. IMI@(CMCS+SL)n demonstrated not only a high loading capacity (exceeding 90 %) but also exhibited exceptional performance in sustained release and anti-termite activity of IMI. Significantly, IMI@(CMCS+SL)n was responsive to both laccase and pH variations. These results suggest that the distinctive laccase activity and weakly alkaline conditions within the termite gut may serve as triggering factors for the release of IMI by IMI@(CMCS+SL)n. Overall, the pesticide carrier system designed in this research ensures precise pesticide application and enhances the value of natural biomass resources.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call