Abstract
Objectives: To establish the effect of small molecule mTOR inhibitors on the tumorigenesis of high-grade papillary serous ovarian cancer (OVCA). To compare the effect of mTOR complex 1 inhibition (mTORiC1) vs. dual mTOR complex 1 and 2 inhibition (mTORCi1+2) with and without Carboplatin (CPP) in an in vitro model of OVCA.
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