Abstract
Purpose: To study tear film changes in patients of Type 2 diabetes mellitus with and without diabetic retinopathy. Method: A hospital based, cross sectional, observational study including 40 patients of Type 2 diabetes mellitus with diabetic retinopathy and 40 patients without diabetic retinopathy. The parameters evaluated for each patient included a questionnaire (based on McMonnie’s Dry Eye questionnaire), Schirmer’s basic secretion test (BST) and Tear film break up time (TBUT). Results: The prevalence of dry eye in patients without diabetic retinopathy was 5% (Schirmer’s BST) and 42.5% (TBUT) as compared to 21.25% (Schirmer’s BST) and 82.5% (TBUT) in patients with diabetic retinopathy. Schirmer’s BST and TBUT were found decreased with the increase in severity of diabetic retinopathy (p<0.001). Conclusions: The prevalence and severity of dry eye, based on clinical parameters, was more in patients with diabetic retinopathy as compared to those without diabetic retinopathy.
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