Abstract
The objective of the present ex-post facto study is to the prevalence of tachyphylaxis in patients using psychotropic drugs. Method: As a quasi-experimental style of study, 100 participants were purposively selected who were admitted to the rehabilitation centre for the treatment of substance-induced disorders, Psychotic disorders, Bipolar disorder and other psychiatric disorders and being treated with medication. The age range was 18 to 60 years. An Urdu-translated version of the Rothschild Scale for Antidepressant Tachyphylaxis (RSAT) was used to find out the prevalence of tachyphylaxis in patients. Results: A significant number of patients were found with tachyphylaxis after treatment of 6 or more than six months as they were being treated with antipsychotics, antidepressants, anxiolytics, tranquillizers and narcotics.
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