Abstract

The present study was conducted to evaluate drug resistance patterns of salmonella enterica serotype typhi and paratyphi in enteric fever. This study is an observational study.

Highlights

  • Enteric fever is commonly known as typhoid fever

  • Isolates of S. enterica serotype typhi resistant to quinolone were reported from same geographical areas with resistance to first line drugs

  • Enteric fever was defined according to gold standard method of isolation of S. enterica serotype typhi and salmonellae enterica serotype paratyphi A

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Summary

Introduction

Enteric fever is commonly known as typhoid fever. Salmonella enterica serotype typhi and salmonellae enterica serotype paratyphi are most common etiological agents of enteric fever. The incubation period varies from 5 to 14 days (Schwartz et al 2012) (Ochiai et al 2008). Isolates of S. enterica serotype typhi resistant to quinolone were reported from same geographical areas with resistance to first line drugs. This was a major threat for treatment of typhoid fever. Somily (2010) reported drug resistant isolates of S. enterica serotype typhi in patient’s returing from travel to Asia (Somily 2010). It is major public health problem and a cause of mortality in Sindh. The present study was aimed to have insight into current trends of drug sensitivity and resistance patterns of S. enterica serotype typhi and salmonellae enterica serotype paratyphi in Sindh province

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