Drug interactions and drug-food interactions in patients receiving diabetes mellitus treatment

Abstract

Drug interaction is the change of a drug's effects by the preceding and/or concurrent administration of a different substance (precipitant drug). Drug interactions may either intensify or weaken the effects that one or both medications are supposed to have. Any drug's therapeutic, preventative, or diagnostic capabilities may change as a result. A major contributing factor to the prevalence and occurrence of adverse medication responses and adverse drug events might be drug interactions. Patients receiving drug combinations or polypharmacy or suffering from co-morbid diseases like diabetes, hypertension, peptic ulcer, fungal infections, and neurodegenerative disorders have a much higher rate of occurrence and incidence of drug interactions. As these patients receive prolonged and multiple treatments, the risk of drug interactions rises. Conclusion: Drug interactions are more likely to occur in diabetes patients who are also getting a mix of medications for diabetic complications. As a result, the frequency of drug interactions is fast increasing. Because of its increasing incidence and the corresponding rise in morbidity and mortality, diabetes mellitus has been regarded as a major public health concern globally. The major goal of this review study is to highlight the different medication interactions that may occur between drugs and foods, as well as to record any unfavorable side effects of other treatments used in conjunction with antidiabetic drugs in diabetic patients.