Drivers of intermittent preventive treatment of malaria during pregnancy in Ghana: a generalized linear model with negative binomial approach

Ernest Yeboah Boateng,Joseph Otoo,Godsway Elorm Anyormi,Daniel A Abaye

doi:10.1186/s40535-018-0057-6

Ernest Yeboah Boateng, Joseph Otoo + Show 2 more

Open Access

https://doi.org/10.1186/s40535-018-0057-6

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Abstract

BackgroundThis study identified the main drivers of intermittent preventive therapy (IPTp) of malaria in pregnancy with the malaria drugs’ sulfadoxine–pyrimethamine (SP) uptake from a longitudinal data set in Ghana.MethodThe data set was obtained from a municipal hospital and spanned a period of 9 years (December 2008–January 2017) and was captured on a monthly basis. We employed the generalized linear modeling approach with negative binomial method to analyze the 9 year data set. A log-linear time-series model was introduced which was then used to validate the results obtained from the logistic model.ResultsIt is evident from the results that antenatal registration of pregnant women, male partner involvement in antenatal clinic attendance, and frequency of visits to antenatal clinics are the key drivers of IPTp-SP uptake.ConclusionsWe recommend that the Family Planning and the Community Health Nursing units of the Ministry of Health, Ghana, should carry effective health campaigns geared towards raising awareness, promoting the early antenatal registration by pregnant women, encourage male partner involvement in antenatal clinics, and increase the frequency of visits (at least 4) to antenatal clinics by the pregnant women to improve upon the low uptake of IPTp-SP in Ghana.

Highlights

Malaria is one of the leading causes of death in many developing nations throughout Africa, South America, and Asia
The implications are that an increase in the proportion of pregnant women who register at antenatal clinics, male involvements at the antenatal clinic, and the number of visits to the antenatal clinic yield the corresponding increase of the uptake of IPT2 by 0.5%, 0.5%, and 0.1%, respectively, with the other variables constant
The results imply that a unit increase in the proportion of pregnant women who register at antenatal clinic corresponds to increase of the uptake of IPT3 for pregnant women by 1.004 holding the other variables constant

Summary

Introduction

Malaria is one of the leading causes of death in many developing nations throughout Africa, South America, and Asia. When the mother is infected during pregnancy, the parasite is passed along with the fetus This event results in stillbirths and low birth weight which is the single greatest risk factor for neonatal deaths. Results: It is evident from the results that antenatal registration of pregnant women, male partner involvement in antenatal clinic attendance, and frequency of visits to antenatal clinics are the key drivers of IPTp-SP uptake. Conclusions: We recommend that the Family Planning and the Community Health Nursing units of the Ministry of Health, Ghana, should carry effective health campaigns geared towards raising awareness, promoting the early antenatal registration by pregnant women, encourage male partner involvement in antenatal clinics, and increase the frequency of visits (at least 4) to antenatal clinics by the pregnant women to improve upon the low uptake of IPTp-SP in Ghana

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Results

Discussion

Conclusion