Abstract
ABSTRACTAn endophytic fungus, Gaeumannomyces sp. strain JS-464, is capable of producing a number of secondary metabolites which showed significant nitric oxide reduction activity. The draft genome assembly has a size of 53,151,282 bp, with a G+C content of 53.11% consisting of 80 scaffolds with an N50 of 7.46 Mbp.
Highlights
An endophytic fungus, Gaeumannomyces sp. strain JS-464, is capable of producing a number of secondary metabolites which showed significant nitric oxide reduction activity
The synthesis of akyl resorcinol and anthraquinone requires a number of genes that are involved in biosynthesis pathways, including the polyketide pathway or the chorismate/o-succinylbenzoic acid pathway [7]
JS-464 was isolated from the rhizome of a reed plant, Phragmites communis, which was collected from a swamp area of Suncheon Bay, South Korea
Summary
Gaeumannomyces sp. strain JS-464, is capable of producing a number of secondary metabolites which showed significant nitric oxide reduction activity. One such endophytic fungus is Gaeumannomyces sp. Strain JS-464, which showed anti-inflammatory activity [6]. This strain produced at least nine compounds, including three new ones that are two new C-glycosylated diakylresorcinol derivatives and a new glycosylated anthraquinone, which showed anti-inflammatory activity in lipopolysaccharide (LPS)-induced BV2 microglial cells [6].
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