Abstract
Faecal concentrations of Lactobacillus GG in human subjects were studied after oral administration of the bacterium Lactobacillus GG was given in total to 44 healthy human volunteers for 7 d as enterocoated tablets with daily doses of 1 x 10 9 c.f.u., 4 x l0 9 and 8 x l0 9 c.f.u. and in fermented milk with daily doses of 2 · 1 x 10 9 c.f.u. and 1 · 2 x 10 10 c.f.u. All the volunteers excreted the organism by day 3 of the test period. There were no statistical differences in mean faecal Lactobacillus GG contents between the tablet groups. With fermented milk there was a clear, statistically significant increase in mean faecal Lactobacillus GG content when the administration was 1 · 2 x 10 10 c.f.u./d compared to 2 · 1 x l0 9 c.f.u./d. The results indicate that fermented milk and enterocoated tablets are good carriers for administering Lactobacillus GG as a probiotic organism. Keywords - Lactobacillus GG; Faecal colonisation; Human probiotic.
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