Abstract
Normal healthy volunteers were given freeze-dried Lactobacillus casei strain GG powder per os once a day for 7 d to study the faecal colonisation properties of the strain. The dose levels administered were 1.5 x 10 6 , 1.5 x 10 7 , 1.5 x 10 8 , 1.5 x 10 9 , 1.5 x 10 10 and 1.1 x 10 11 c.f.u./day. A comparison of the colonisation properties between production lots was made using three different lots. Faecal specimens were collected both prior to ' Lactobacillus GG' administration and daily during the respective treatments. Faecal specimens were analysed for total lactobacilli and ' Lactobacillus GG'. No ' Lacrobacillus GG' was detected in the faecal samples of the volunteers prior to the study. With the doses 10 10 and 10 11 all volunteers were colonised. ' Lactobacillus GG' did not appear to influence the total number of lactobacilli in faeces. No significant differences were found between production lots. Keywords: Lactobacillus casei ; Lactobacillus GG; Faecal colonisation.
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