Dopamine Accumulation in Papaver somniferum Latex

Abstract

Abstract Organelles found in the 1000 x g fraction of latex taken from Papaver somniferum have been shown to accumulate dopamine to the exclusion of other catecholamines. Dopamine accumula­ tion is both temperature and pH dependent and there is no evident requirement for ATP (1 mᴍ) or Mg2+ (2mᴍ). The relatively high (4.37 mᴍ), specificity of dopamine uptake, and insensitivity to inhibitors distinguish papaver latex organelle dopamine uptake from catecholamine uptake by mammalian chromaffin granules.