Abstract
Some epidemiological studies reported that sunlight exposure and highvitamin D levels may decrease the morbidity and mortality related to cancer. We aimed to evaluate whether sunlight exposure has an impact on survival in patients with non small cell lung cancer. A total of 546 patients with NSCLC from two different regions (Kayseri and Adana) differing according to sunlight exposure were analysed retrospectively. The median overall survival (OS) rates were 11. 6 (CI: 9.50-13.6) and 15.6 months (CI: 12.4-18.8) for Kayseri and Adana, respectively, in all patients (p=0.880). There were no differences between groups in terms of OS. While there is strong evidence regarding inverse relationship between cancer incidence and sunlight exposure, it is still controversial whether sunlight exposure is a good prognostic factor for survival in patients with lung cancer.
Highlights
Lung cancer is the leading cause of cancer related deaths in both men and women (Jemal et al, 2011; Demirci et al, 2013)
Some epidemiological studies reported that sunlight exposure and highvitamin D levels may decrease the morbidity and mortality related to cancer
We aimed to evaluate whether sunlight exposure has an impact on survival in patients with non small cell lung cancer
Summary
Lung cancer is the leading cause of cancer related deaths in both men and women (Jemal et al, 2011; Demirci et al, 2013). It was speculated that sufficient solar light exposure and vitamin D level may decrease the morbidity and mortality related to cancer. When it was evaluated some studies about the relationship between geographical or seasonal differences and lung cancer, in a study, it was reported that the lower levels of ultraviolet B irradiance were independently associated with higher incidence rates of lung cancer in countries (Mohr et al, 2008). We aimed to evaluate whether sunlight exposure has an impact on survival in patients with non small cell lung cancer. Materials and Methods: A total of 546 patients with NSCLC from two different regions (Kayseri and Adana) differing according to sunlight exposure were analysed retrospectively. While there is strong evidence regarding inverse relationship between cancer incidence and sunlight exposure, it is still controversial whether sunlight exposure is a good prognostic factor for survival in patients with lung cancer
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