Does Solfinacin solve the urgency symptoms in postpartum women ?

Abstract

Background: It is widely accepted that antimuscarinics are considered first-line treatment for patients with overactive bladder (OAB). However, the mechanism by which antimuscarinics improve the symptoms of OAB remains to be fully elucidated. Patients and methods: This study is a clinical prospective follow-up study carried out in the Consultancy Clinic of Al-Elwiya Maternity Teaching Hospital in Baghdad-Iraq. duration(November, 2019-April, 2020). inclusion criteria were adult postpartum women at childbearing age with symptoms of the overactive bladder treated by a Gynecologist with Solifenacin tablets. Results: a current study showed 34% of them were in the age group 20-29 years. The mean parity history of women with OAB was (3); 32% of them had a parity history of 1-3 para and 68% of them had a parity history of 4-6 para. delivery mode for 84% of women with OAB was a vaginal delivery, as well as 36% of women with OAB, had ≤7 times urinations a day, as well as a significant decline in score 2 observed after treatment with Solifenacin (p=0.01). No significant differences were observed in score 3 before and after Solifenacin treatment (p=0.06). A significant decline in score 4 was observed after treatment with Solifenacin (p=0.001). No significant differences were observed in women with OAB before and after Solifenacin treatment, soa highly significant increase in control of urination after treatment (p<0.001). Conclusion: solifenacin drug is effective in the reduction of overactive bladder syndrome score three months after treatment.