Does gender selection works? An observational study

Abstract

Sex selection is an option for couples who want to avoid passing a sex- linked genetic disease to their baby. For example, some females are carriers for over 350 X-linked diseases, even if the disease does not directly affect them. Hemophilia and Duchenne muscular dystrophy are examples of diseases that occur with a recessive gene on the X chromosome. Some choose the sex of their baby because of a personal preference like "Family balancing." Many studies were done before to prefer one gender upon another. When we look at the statistics the chances of having a boy or a girl are almost the same and there is no medical evidence to suggest we can influence Design: Prospective randomized controlled study. Setting: The study was conducted at LAMIS Clinic for Obstetrics & Gynecology from January 2015 to February 2022 and still continue up today. The study started after observation that use of cyclofert female capsules before conceptions leads to more probability to male sex embryos. Our study contains five thousand patients who received cyclofert female capsules at dose of two capsules per day for at least two months before conceptions. The data was compared with another one thousands patients who receive placebo. The two groups divided into three according to the age group. All patient included were on natural cycles and no ovulation inductions used, irrespective of the parity. Objectives: To rule out that the observation which is noted that increase male gender embryos related to use of cyclofertfemal capsules or not. Results: The overall pregnancy rate irrespective of the age was 86.02% (4301/5000) & 66.6% (666/1000) for the cyclofert group and the placebo group respectively. Overall abortion rate for cyclofert group was 1.4% (60/4301) while 9.3% (62/666) for placebo group. 89.69% (3804/4241) of the total pregnancy were male gender in cyclofert Group, while at placebo group it was 41.23 % (249/604), (p<0.05 statistically significant). Conclusion: Gender selection could be work by non-invasive, not expensive, effective, affordable, and available without complication method by giving cyclofert female capsules, which is, increases the pregnancy rate, reduces the rate of abortion and increases the male gender embryos. Although, there is no guarantee that the baby will actually be one sex or the other, but cyclofertfemal capsules can influence what type of sperm cell will reach an ovum, and fertilize it. Therefore, yes, male gender selection may be technically possible.