Abstract
An optical image processing technique is proposed for analyzing and exploring DNA sequences. The proposed approach uses the powerful computing capability of optical correlation to provide real-time processing of the genomic data. Instead of representing the symbolic DNA sequences in numeric form, they are converted and treated as 2-D images for matching purposes. Both images of the reference and the target DNA sequences are combined and presented as a joint input image to an optical joint transform correlator (JTC) set-up for a real-time processing. This JTC-based approach is capable to search for similarity/dissimilarity between two tested DNA sequences. The proposed optical approach facilitates the exhaustive search algorithms for locally and/or globally DNA alignment. Simulations experimental results on actual DNA sequences are presented to demonstrate the effectiveness of the proposed optical approach.
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