Abstract

ABSTRACT In this study, the potential genotoxic and mutagenic effects of cocoa industry wastewater was assessed using SOS Chromo and Ames fluctuation tests, respectively. The physico-chemical analyses of the wastewater were also carried out. The SOS Chromo and Ames fluctuation tests results showed that cocoa industry wastewater can induce different levels of DNA damage and mutagenic potential at the different concentrations used in this study. Salmonella typhimurium TA98 was more sensitive than TA100 strain, indicating frameshift mutation as a possible mechanism of DNA damage. High concentrations of Pb, Cd, Cr, Ni and Cu in the tested sample were possibly responsible for the observed mutagenicity and genotoxicity.

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