Abstract
Objective: The aim of study was to determine whether idiopathic polyhydramnios is in relation with dynamic thiol-disulfide homeostasis and ischemia modified albumin levels or not. 
 Materials and methods: In this prospective case- control study, a total of 126 participants were included. The patient group consisted of 56 patients who were diagnosed idiopathic polyhydramnios, and the control group consisted of 56 healthy normal pregnant. Native thiol (-SH), total thiol (-SH. -SS), dynamic disulfide (-SS), values from maternal serum were measured and compared between groups.
 Results: 112 patients aged between 18-35 years, consisting of 56 idiopathic polyhydramnios and 56 control groups were included in the study. Maternal serum native and total thiol values were significantly higher in study group compared to control group (382.2 ±78.5 mmol/L vs. 331.8 ±43.9 mmol/L, p
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