Abstract
Diversity-oriented synthesis of 2, 5-diketopiperazines was accomplished via Ugi/aza-Michael reaction cascades in one pot. The intramolecular hydrogen bonding between the heteroatom (O or N) from the aldehyde component and the amide -NH group facilities the aza-Michael transformation. This protocol offers a straightforward and concise method to build diversified 2, 5-diketopiperazines library for drug discovery.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: IOP Conf. Series: Materials Science and Engineering
Paper Title
Journal
Date
