Diverse Interactions of N-Methyl Glycine in Aqueous Paracetamol Solution with the Manifestation of Solvation Consequences

Abstract

The apparent molar volume (ϕV) and viscosity B-coefficient of N-methyl glycine of 0.01 M, 0.02 M and 0.03 M aqueous solutions have been estimated in presence of paracetamol at three temperatures namely 298.15 K, 303.15 K and 308.15 K from physicochemical study such as density (ρ) and viscosity (η) and refractive index measurements and 1 H NMR spectroscopy. The volumetric study was employed to evaluate limiting apparent molar volumes (ϕ V 0 ) and experimental slopes (S V *) by using Masson equation for explaining solute–solvent and solute–solute interactions, respectively. The nature of group interactions between the solute, solvent and co-solute have been examined from limiting apparent molar volumes of transfer (Δϕ V 0 ) values. The viscosity data were employed to determine viscosity A and B coefficients from Jones–Dole equation and the resulting parameters were used to examine the solute–solute and solute–solvent interactions in the solutions. Molar refraction values calculated from refractive indices by applying Lorentz–Lorenz equation were used to depict the intermolecular interactions between N-methyl glycine and paracetamol in their aqueous solution. However, the 1 H NMR spectroscopy supports the existence of diverse interactions concretely.